Intramural Research

What this funds

The Division of Intramural Research Programs (IRP) is the internal research component of NIMH, complementing the institute's extramural grant funding program. IRP scientists investigate basic, translational, and clinical aspects of brain function and behavior across the lifespan, conducting state-of-the-art research using unique NIH resources. In addition, the IRP provides an excellent environment for training the next generation of basic, translational, and IRP researchers use sophisticated experimental techniques (such as optogenetic stimulation and two-photon imaging) to study brain circuit function and behavior. Researchers are also behavior may point towards treatments that target dysregulation of these circuits in neuropsychiatric disorders.11 Other IRP scientists are interested in looking at the autoimmune underpinnings of some neuropsychiatric conditions. IRP scientists are exploring novel medications and other treatments for mood disorders in adults, including research on the efficacy and safety of fast-acting treatments like ketamine and magnetic-seizure therapy - which have been shown to rapidly decrease acute symptoms. IRP researchers also continue to study youth Predicting future hospital visits: In a recent study, IRP researchers validated the NIMH- developed Ask Suicide-Screening Questions (ASQ) tool in emergency departments and inpatient and outpatient primary care settings and demonstrated that the tool can help predict future- suicide-related hospital visits. The tool has also been translated into 32 languages and validated in Spanish, Japanese, and Korean. The ASQ is also being adapted and tested for use in a variety of settings and populations, including youth with autism and other neurodevelopmental Developing behavioral therapy for children: Researchers developed a novel treatment for Irritability and outbursts are part of many mental disorders, but they are core symptoms of disruptive mood dysregulation disorder (DMDD). Children received 12 sessions of CBT, during which clinicians carefully exposed children to anger-provoking situations and worked with children to learn to tolerate and constructively respond without outburst. Clinicians found that the irritability symptoms decreased significantly during treatment and gains were maintained several months after treatment ended. This study set the foundation to further explore CBT Budget Policy: The FY 2027 President's Budget request for the NIMH intramural research Research Management and Support (RMS) activities provide administrative, budgetary, logistical, and scientific support in the review, award, and monitoring of research and training grants, and research and development contracts. RMS functions include strategic planning, coordination, and evaluation of NIMH programs, regulatory compliance, coordination of global mental health efforts, and liaising with other Federal agencies, Congress, and the public. Staff also play key roles in coordinating NIMH's involvement in the NIH BRAIN Initiative and in managing related research. Through RMS activities, NIMH continues to provide accountability and administrative support for meritorious basic, clinical, and translational research and promote health information dissemination, education, and outreach activities. RMS also supports outreach activities to connect the public with evidence-based mental health information. Budget Policy: The FY 2027 President's Budget request for RMS activities is $105.3 million, a decrease of $8.8 million or 7.7 percent compared with the FY 2026 Enacted level. 1 The FY 2026 President's Budget proposed consolidating the 27 NIH Institutes and Centers into an 8- Institute structure, while maintaining the Office of the Director and the Building and Facilities account. 2 Includes funds derived by transfer from the NIH Innovation Account under the 21st Century Cures Detail of Full-Time Equivalent Employment (FTE)

Extracted from NIH - National Institute of Mental Health, p. 11. Verbatim; nothing here is paraphrased.

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