# Chemical and Biological Defense Program — Program Element 0601384BP

**Program element:** 0601384BP  
**Component:** Defense-Wide  
**Appropriation:** 0400 — RDT&E, Defense-Wide  
**Budget Activity:** 1 — Basic Research  
**Vintage:** President's Budget PB2027  
**Canonical URL:** https://hitchintel.com/programs/0601384BP

## Summary

Defense-Wide requests $27.4M in FY2027. In the FY2027 defense authorization, the House funded it in full; the Senate funded it in full; House appropriators funded it in full.

## Funding profile

| Fiscal Year | Estimate Type | Amount ($M) |
|---|---|---|
| FY2025 | Actual | 37.0 |
| FY2026 | Enacted | 28.2 |
| FY2027 | Request | 27.4 |
| FY2028 | Outyear | 24.9 |
| FY2029 | Outyear | 24.0 |
| FY2030 | Outyear | 23.6 |
| FY2031 | Outyear | 23.4 |

> Estimate types are not summed — the profile mixes actuals, enacted law, the request, and outyear projections.

## Congressional marks (FY2027)

| Stage | Marked ($M) | Change ($M) |
|---|---|---|
| Request | 27.4 | — |
| House NDAA (HASC) | 27.4 | +0.0 |
| Senate NDAA (SASC) | 27.4 | +0.0 |
| House Approps (HAC-D) | 27.4 | +0.0 |

> FY2027 NDAA authorization marks, as of 2026-07-27. Not appropriations or final law.

## Projects (2)

| Project | Title | FY2025 actual | FY2026 enacted | FY2027 request | Move |
|---|---|---|---|---|---|
| LF1 | Life Sciences (Basic Research) | 20.4 | 17.7 | 16.1 | −9% |
| PS1 | Physical Sciences (Basic Research) | 16.5 | 10.6 | 11.3 | +7% |

> Projects are the summable leaves: the program element total is their sum, never added to it.

### Project LF1 — Life Sciences (Basic Research)

This Project (LF1) focuses on fundamental efforts to understand living systems' responses to biological or chemical agents to support detection, protection, diagnostics, and medical treatment. Research focuses on studying factors that influence the behavior of chemicals, toxins, and pathogens in relation to the host or target. Understanding host/agent interactions can drive the exploration of novel approaches to detect, diagnose or protect against threats. Research also focuses on medical countermeasures for improved efficacy against a wide array of current and future threat agents. This project is a key enabler supporting the Understand, Protect, and Mitigate portfolios.

| Activity (R-2A) | FY2025 | FY2026 | FY2027 |
|---|---|---|---|
| 1) Life Sciences | 20.4 | 17.7 | 16.1 |

> R-2A activities carry the prior, current and budget year only — no five-year plan. Coverage is partial, so count them, never total them.

### Project PS1 — Physical Sciences (Basic Research)

This Project (PS1) advances fundamental scientific knowledge in physical science areas that include chemistry, physics, materials science, environmental science, and nanotechnology that could potentially lead to transformational chemical and biological (CB) defensive capabilities enhancing warfighter performance and safety. This project is a key enabler supporting the Understand, Protect, and Mitigate portfolios.

| Activity (R-2A) | FY2025 | FY2026 | FY2027 |
|---|---|---|---|
| 1) Physical Sciences | 16.5 | 10.6 | 11.3 |

> R-2A activities carry the prior, current and budget year only — no five-year plan. Coverage is partial, so count them, never total them.

## Mission & acquisition strategy

This program element (PE) resources basic research efforts directed at promoting theoretical and experimental research in Life and Physical Sciences. These efforts are part of an integrated portfolio addressing emerging chemical and biological (CB) threats, and are a key enabler supporting the Understand, Protect, and Mitigate portfolios. Basic research focuses on pursuing fundamental science to advance a greater understanding of threats, improve situational awareness of emerging threats, and support transformative research in emerging research areas that can potentially foster paradigm shifts in the CB defense research arena to a rapid response capability.

## Related program elements

- [0601121A — Cyber Collaborative Research Alliance](https://hitchintel.com/programs/0601121A) (Army)
- [0604009F — Afwerx](https://hitchintel.com/programs/0604009F) (Air Force)
- [0603384BP — Chemical and Biological Defense Program - Advanced Development](https://hitchintel.com/programs/0603384BP) (Defense-Wide)
- [0605384BP — Chemical and Biological Defense Program](https://hitchintel.com/programs/0605384BP) (Defense-Wide)

## Source & machine access

- **Source:** FY2027 Office of the Secretary of Defense RDT&E Budget Justification, Exhibits R-2/R-3, PE 0601384BP (PB PB2027); FY2027 NDAA committee marks (as of 2026-07-27).
- **MCP:** `mcp.hitchintel.com` — `budget_get_program_element(pe="0601384BP")`.

*HitchAI is an independent intelligence service, not affiliated with the U.S. Department of Defense. Budget figures are requests/estimates, not obligations.*