# Chemical and Biological Defense Program - Advanced Development — Program Element 0603384BP

**Program element:** 0603384BP  
**Component:** Defense-Wide  
**Appropriation:** 0400 — RDT&E, Defense-Wide  
**Budget Activity:** 3 — Advanced Technology Development  
**Vintage:** President's Budget PB2027  
**Canonical URL:** https://hitchintel.com/programs/0603384BP

## Summary

Defense-Wide funding ramps 29% to a $310.3M request in FY2027 — the program's peak. In the FY2027 defense authorization, the House funded it in full; the Senate funded it in full; House appropriators funded it in full.

## Funding profile

| Fiscal Year | Estimate Type | Amount ($M) |
|---|---|---|
| FY2025 | Actual | 230.2 |
| FY2026 | Enacted | 241.0 |
| FY2027 | Request | 310.3 |
| FY2028 | Outyear | 244.9 |
| FY2029 | Outyear | 245.9 |
| FY2030 | Outyear | 244.7 |
| FY2031 | Outyear | 247.5 |

> Estimate types are not summed — the profile mixes actuals, enacted law, the request, and outyear projections.

## Congressional marks (FY2027)

| Stage | Marked ($M) | Change ($M) |
|---|---|---|
| Request | 310.3 | — |
| House NDAA (HASC) | 310.3 | +0.0 |
| Senate NDAA (SASC) | 310.3 | +0.0 |
| House Approps (HAC-D) | 310.3 | +0.0 |

> FY2027 NDAA authorization marks, as of 2026-07-27. Not appropriations or final law.

## Projects (5)

| Project | Title | FY2025 actual | FY2026 enacted | FY2027 request | Move |
|---|---|---|---|---|---|
| UN3 | Understand (ATD) | 76.7 | 86.5 | 93.3 | +8% |
| EN3 | Enabling Investments (ATD) | 17.0 | 18.5 | 89.3 | +383% |
| MT3 | Mitigate (ATD) | 77.1 | 80.7 | 59.2 | −27% |
| PT3 | Protect (ATD) | 46.9 | 46.3 | 57.5 | +24% |
| ET3 | Emerging Threats (ATD) | 12.5 | 9.0 | 11.0 | +22% |

> Projects are the summable leaves: the program element total is their sum, never added to it.

### Project UN3 — Understand (ATD)

The Understand Advanced Technology Development (ATD) Project supports freedom of maneuver and informs commanders' decisions by predicting, locating, identifying, analyzing, and warning of chemical and biological (CB) hazards. Thrust Areas included in this Project are: (1) Chemical, Biological, Radiological, and Nuclear (CBRN) Battlespace Sensing, Alerting & Response (2) CBRN Decision Aids (3) CBRN Situational Awareness (4) CBRN Battlespace Sensing, Alerting, and Response - Enhanced Biological Defense (5) CBRN Decision Aids - Enhanced Biological Defense (6) CBRN Situational Awareness - Enhanced Biological Defense (7) Operational Diagnostics (8) Clinical Evaluation (9) Diagnostic Building Blocks (10) Emerging Threats (11) Emerging and Enhanced Biothreat Sensing - Waste Water Surveillance (12) Operational Chemical Sensing - Chemical Detection (13) Modernized and Enhanced Chemical Sensing - Chemical Detection (14) Unconventional Detection Modalities - Chemical Detection (15) Operational Biological Sensing - Biological Detection (16) Emerging and Enhanced Biothreat Sensing - Biological Detection (17) Unconventional Detection Modalities - Biological Detection

| Activity (R-2A) | FY2025 | FY2026 | FY2027 |
|---|---|---|---|
| 1) Chemical Biological Radiological Nuclear Battlespace Sensing, Alerting, and Response | 4.6 | 6.2 | 5.8 |
| 2) Chemical Biological Radiological Nuclear Decision Aids | 3.5 | 5.7 | 7.3 |
| 3) Chemical Biological Radiological Nuclear Situational Awareness | 5.2 | 5.6 | 12.9 |
| 4) Chemical Biological Radiological Nuclear Battlespace Sensing, Alerting, and Response - Enhanced Biological Defense | 1.0 | 1.0 | 0.8 |
| 5) Chemical Biological Radiological Nuclear Decision Aids - Enhanced Biological Defense | 1.0 | 1.0 | 0.5 |
| 6) Chemical Biological Radiological Nuclear Situational Awareness - Enhanced Biological Defense | — | — | 0.8 |
| 7) Operational Diagnostics | 13.1 | 12.4 | 13.1 |
| 8) Clinical Evaluation | 2.8 | 1.8 | 1.0 |
| 9) Diagnostic Building Blocks | 9.4 | 7.3 | 7.8 |
| 10) Emerging Threats | 5.7 | 4.7 | 1.9 |
| 11) Emerging and Enhanced Biothreat Sensing - Waste Water Surveillance | 5.1 | 9.2 | 7.5 |
| 12) Operational Chemical Sensing - Chemical Detection | 2.8 | 2.9 | 16.9 |
| 13) Modernized and Enhanced Chemical Sensing - Chemical Detection | 12.8 | 16.8 | 7.5 |
| 14) Unconventional Detection Modalities - Chemical Detection | 2.2 | 2.3 | 1.0 |
| 15) Operational Biological Sensing - Biological Detection | 2.4 | 2.8 | 1.5 |
| 16) Emerging and Enhanced Biothreat Sensing - Biological Detection | 4.1 | 5.9 | 7.1 |
| 17) Unconventional Detection Modalities - Biological Detection | 0.8 | 1.0 | — |

> R-2A activities carry the prior, current and budget year only — no five-year plan. Coverage is partial, so count them, never total them.

### Project EN3 — Enabling Investments (ATD)

The Enabling Investments Advanced Technology Development (ATD) Project focuses on early and continued involvement of the warfighter in the technology development process and has implemented a user community engagement process to align science and technology (S&T) activities with operational needs and ensure functional design. This process begins with the identification of an innovative technology concept, continues through the assessment of the prototype, and ends at the operational and utility demonstrations to enhance transition to an advanced developer. Enabling efforts in this area support dedicated infrastructure capabilities, demonstrations, and overarching development support functions as portfolio enablers responding to emerging threats. Thrust Areas included in this Project are: (1) Biological Warfare Defense Prophylaxis (2) Forward Element Experimentation and Prototyping (3) Forge High Performance Computing (FHPC) (4) Advanced Technology Demonstration (ATD) (5) Technology Concepts (6) User Assessment

| Activity (R-2A) | FY2025 | FY2026 | FY2027 |
|---|---|---|---|
| 1) Biological Warfare Defense Prophylaxis | 7.2 | 7.5 | 7.5 |
| 2) CBRND Forward Element Experimentation and Prototyping | — | — | 11.0 |
| 3) Forge High Performance Computing | — | — | 60.0 |
| 4) Advanced Technology Demonstration | 6.2 | 6.1 | 6.2 |
| 5) Technology Concepts | 1.8 | 3.0 | 2.6 |
| 6) User Assessment | 1.9 | 1.9 | 2.0 |

> R-2A activities carry the prior, current and budget year only — no five-year plan. Coverage is partial, so count them, never total them.

### Project MT3 — Mitigate (ATD)

The Mitigate Advanced Technology Development (ATD) Project provides the Joint Force the ability to preserve combat power by mitigating exposure to chemical and biological (CB) hazards and restoring combat readiness of critical personnel and platforms. Thrust Areas included in this Project are: (1) Biological Warfare Defense Therapeutics (2) Biological Warfare Defense Therapeutics - Enhanced Biological Defense (3) Discovery of Medical countermeasures Against New and Emerging threats - Enhanced Biological Defense (4) Chemically Reactive Ocular, Wound and Dermal Therapeutics (5) Emerging and Pharmaceutical-based Agent Threats (6) Reactivators of Acetylcholinesterase as Therapeutics (7) Critical Area Decontamination (8) Equipment Decontamination (9) Multifunctional Materials for Protection (10) Enhanced Survivability Coatings (11) Personnel Decontamination (12) Equipment Decontamination - Enhanced Biological Defense (13) Critical Area Decontamination - Enhanced Biological Defense

| Activity (R-2A) | FY2025 | FY2026 | FY2027 |
|---|---|---|---|
| 1) Biological Warfare Defense Therapeutics | 21.1 | 22.9 | 18.2 |
| 2) Biological Warfare Defense Therapeutics - Enhanced Biological Defense | 20.9 | 20.0 | 20.0 |
| 3) Discovery of Medical countermeasures Against New and Emerging threats - Enhanced Biological Defense | 13.4 | 11.6 | 2.5 |
| 4) Chemically Reactive Ocular, Wound and Dermal Therapeutics | 2.4 | 5.5 | — |
| 5) Emerging and Pharmaceutical-based Agent Threats | 1.4 | 1.7 | — |
| 6) Reactivators of Acetylcholinesterase as Therapeutics | 6.5 | 9.5 | 3.0 |
| 7) Critical Area Decontamination | 0.8 | 0.8 | 0.8 |
| 8) Equipment Decontamination | 1.3 | 3.5 | 8.6 |
| 9) Multifunctional Materials for Protection | 0.1 | 0.1 | 0.1 |
| 10) Enhanced Survivability Coatings | 0.1 | — | — |
| 11) Personnel Decontamination | 3.1 | 5.0 | — |
| 12) Equipment Decontamination - Enhanced Biological Defense | 5.0 | 0.2 | 5.0 |
| 13) Critical Area Decontamination - Enhanced Biological Defense | 1.0 | — | 1.0 |

> R-2A activities carry the prior, current and budget year only — no five-year plan. Coverage is partial, so count them, never total them.

### Project PT3 — Protect (ATD)

The Protect Advanced Technology Development (ATD) Project enhances mission performance while providing effective protection against current and emerging chemical and biological (CB) threats, enables Joint Force lethality by protecting warfighters against adverse effects of CB hazards, and fields interim protection capabilities against engineered biological agents, opioids and other Pharmaceutical Based Agents (PBAs), and Fourth Generation Agents (FGAs). Thrust Areas included in this Project are: (1) Biological Warfare Defense Prophylaxis (2) Nerve Agent Prophylaxis (3) Air Purification Enhancements (4) All-Hazards and Respiratory Protection (5) Enhanced Survivability Coatings (6) Multifunctional Materials for Protection (MMfP) (7) Protective Garments (8) Air Purification Enhancements - Enhanced Biological Defense (9) All-hazards and Respiratory Protection - Enhanced Biological Defense (10) Protective Garments - Enhanced Biological Defense

| Activity (R-2A) | FY2025 | FY2026 | FY2027 |
|---|---|---|---|
| 1) Biological Warfare Defense Prophylaxis | 23.8 | 27.9 | 23.6 |
| 2) Nerve Agent Prophylaxis | 12.1 | 10.2 | 24.0 |
| 3) Air Purification Enhancements | 0.6 | 0.8 | 0.8 |
| 4) All-Hazards and Respiratory Protection | 1.6 | 1.8 | 2.9 |
| 5) Enhanced Survivability Coatings | 0.4 | — | — |
| 6) Multifunctional Materials for Protection | 0.3 | 0.2 | 0.2 |
| 7) Protective Garments | 4.1 | 1.6 | 4.1 |
| 8) Air Purification Enhancements - Enhanced Biological Defense | 2.0 | 2.0 | 2.0 |
| 9) All-hazards and Respiratory Protection - Enhanced Biological Defense | 1.0 | 0.9 | — |
| 10) Protective Garments - Enhanced Biological Defense | 1.0 | 1.0 | — |

> R-2A activities carry the prior, current and budget year only — no five-year plan. Coverage is partial, so count them, never total them.

### Project ET3 — Emerging Threats (ATD)

Project ET3 aims to identify and develop scientific solutions, or to modernize capabilities, that allow for a more rapid response to emerging threats. This project supports the development of defense capabilities, collaborating across the Department of War (DoW) and specific interagency partners for doctrine, equipment, and training for the warfighter and civilian population for defense against emerging threats. Additionally, this project supports advanced development of defensive science and technology capabilities aimed at proactive characterization of threats and potentially disruptive technologies.

| Activity (R-2A) | FY2025 | FY2026 | FY2027 |
|---|---|---|---|
| 1) Emerging Threat Innovation | 12.5 | 9.0 | 11.0 |

> R-2A activities carry the prior, current and budget year only — no five-year plan. Coverage is partial, so count them, never total them.

## Mission & acquisition strategy

This program element (PE) resources Advanced Technology Development across the Understand, Protect, Mitigate, and Enabling Investments portfolios. Chemical and Biological Defense Program (CBDP) investments provide an integrated, layered capability to enable Department of War (DoW) missions in a chemical and biological environment, ranging from combat operations to domestic incident prevention and response. The Projects in this PE demonstrate technologies supporting the transition to advanced component development for physical capabilities, which cover chemical and biological (CB) detection, situational awareness and effects modeling, and protection and hazard mitigation.

## Related program elements

- [0602384BP — Chemical and Biological Defense Program](https://hitchintel.com/programs/0602384BP) (Defense-Wide)
- [0607384BP — Chemical and Biological Defense (Operational Systems Development)](https://hitchintel.com/programs/0607384BP) (Defense-Wide)
- [0604245M — H-1 Upgrades](https://hitchintel.com/programs/0604245M) (Navy)
- [0604134A — Counter Improvised-Threat Demonstration, Prototype Development, and Testing](https://hitchintel.com/programs/0604134A) (Army)

## Source & machine access

- **Source:** FY2027 Office of the Secretary of Defense RDT&E Budget Justification, Exhibits R-2/R-3, PE 0603384BP (PB PB2027); FY2027 NDAA committee marks (as of 2026-07-27).
- **MCP:** `mcp.hitchintel.com` — `budget_get_program_element(pe="0603384BP")`.

*HitchAI is an independent intelligence service, not affiliated with the U.S. Department of Defense. Budget figures are requests/estimates, not obligations.*