R-2A Activity · President's Budget PB2027

8) Nerve Agent Prophylaxis

FY2027 Request
$21.1M
▲ 548% vs FY2026
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This activity requests $21.1M in FY2027, 27% of project PT2, up 548% on FY2026. The R-2A exhibit describes it across FY2025–FY2027, including what the FY2027 money is planned to buy.

FY2027 Request
$21.1M
▲ 548% vs FY2026
FY2026 Enacted
$3.3M
▼ 14% vs FY2025
FY2025 Actual
$3.8M
Prior year
Planned work

What the FY2027 request buys

Verbatim from the R-2A exhibit for project PT2 of PE 0602384BP. This is the budget justification's own description of work that has not happened yet — the one thing no other level of the budget carries.

FY2027 planned work

- Continue the identification and development of lead medicine candidates. - Additional drug candidates that utilize several different technical approaches will be pursued.

FY2026 to FY2027 change

Program/project funding transferred from another funding line. Funding transferred from Project MT2/Mitigate to pursue additional Nerve Agent Prophylaxes drug candidates.

Before the request year

FY2025–FY2026: what came before

Prior-year accomplishments and current-year plans from the same exhibit. Context for the FY2027 plan, not a series — an activity partitions its project exactly in the request year, but can under-cover it in earlier years.

FY2026 plans — current year

- Complete vaccine efficacy studies against multiple agents. - Continue to develop one or more alternative nerve agent prophylactic technologies as a risk mitigation step

FY2025 accomplishments

- Continued the identification and development of lead medicine candidates. Multiple candidates were pursued. - Continued to perform studies on how well the protective medicines work (efficacy), how they move into, through and out of the body (pharmacokinetics), and if there are any significant harmful effects (toxicity).

Money

Three years, and no five-year plan

An R-2A activity publishes the prior year, the current year and the budget year. The FYDP outyears exist at project and program-element level and are deliberately absent here rather than inferred. Estimate types are colored and never summed into one figure.

03.8FY25ACTUAL3.3FY26ENACTED21.1FY27REQUEST
Actual Enacted Request
Fiscal YearEstimate TypeAmount ($M)
FY2025Actual3.8
FY2026Enacted3.3
FY2027Request21.1

This activity is 27% of project PT2's FY2027 request and 10% of PE 0602384BP's. In the request year the activities under a project sum to it exactly; in the current year they under-cover it in about 9% of cases, so an activity's delta can legitimately exceed its parent's and the two must not be compared row to row.

Where this sits

8 activities in project PT2

Every R-2A line of this project, largest FY2027 request first. Linked where the activity has enough of its own narrative to carry a page; the rest are shown in full on the project page.

8) Nerve Agent Prophylaxis — this activity$21.1M ▲ 548%
2) Biological Warfare Defense Prophylaxis - Enhanced Biological Defense$20.9M flat1) Biological Warfare Defense Prophylaxis$20.9M ▲ 27%
5) Multifunctional Materials for Protection$8.5M ▲ 114%
6) Protective Garments$3.3M ▼ 11%
4) All-Hazards and Respiratory Protection$1.9M ▲ 28%
3) Air Purification Enhancements$1.4M flat
7) Enabling Science▼ 100%
Source
FY2027 Office of the Secretary of Defense RDT&E Budget Justification · Exhibit R-2A · PE 0602384BP, project PT2 (President's Budget PB2027). Congressional marks are recorded on the program element, never on an activity.
Machine access
Markdown twin /programs/0602384BP/PT2/a7.md · MCP mcp.hitchintel.combudget_get_activity