R-2A Activity · President's Budget PB2027

Novel Delivery Technology for Medical Countermeasures

FY2027 Request
$12.1M
▼ 36% vs FY2026
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This activity requests $12.1M in FY2027, 6.4% of project WP-02, down 36% on FY2026. The R-2A exhibit describes it across FY2026–FY2027, including what the FY2027 money is planned to buy.

FY2027 Request
$12.1M
▼ 36% vs FY2026
FY2026 Enacted
$19.0M
In law
Planned work

What the FY2027 request buys

Verbatim from the R-2A exhibit for project WP-02 of PE 0602024E. This is the budget justification's own description of work that has not happened yet — the one thing no other level of the budget carries.

FY2027 planned work

- Demonstrate delivery of countermeasure cargo in additional cell types. - Demonstrate systemic delivery of countermeasure cargo. - Develop and demonstrate scale-up manufacturing of the highest-performing delivery vehicles. - Demonstrate delivery of two or more MCM modalities.

FY2026 to FY2027 change

The FY 2027 decrease reflects a reduction in research and development activities to conduct verification and validation studies of candidate countermeasure delivery vehicles.

Before the request year

FY2026: the year under way

Prior-year accomplishments and current-year plans from the same exhibit. Context for the FY2027 plan, not a series — an activity partitions its project exactly in the request year, but can under-cover it in earlier years.

FY2026 plans — current year

- Demonstrate that the delivery chassis and formulation strategies are capable of delivering countermeasures to multiple cell types experimentally and in whole organisms. - Deliver countermeasure cargo in vivo using a simple administration method. - Assess the safety of the delivery chassis (e.g., minimal adverse effects) in vivo. - Measure the duration of protection following countermeasure administration using the delivery chassis.

Money

Three years, and no five-year plan

An R-2A activity publishes the prior year, the current year and the budget year. The FYDP outyears exist at project and program-element level and are deliberately absent here rather than inferred. Estimate types are colored and never summed into one figure.

019.0FY26ENACTED12.1FY27REQUEST
Enacted Request
Fiscal YearEstimate TypeAmount ($M)
FY2026Enacted19.0
FY2027Request12.1

This activity is 6.4% of project WP-02's FY2027 request and 3.3% of PE 0602024E's. In the request year the activities under a project sum to it exactly; in the current year they under-cover it in about 9% of cases, so an activity's delta can legitimately exceed its parent's and the two must not be compared row to row.

Where this sits

14 activities in project WP-02

Every R-2A line of this project, largest FY2027 request first. Linked where the activity has enough of its own narrative to carry a page; the rest are shown in full on the project page.

Biomedical Technology Studies and Concepts$57.2M ▲ 453%Generative Optogenetics (GO)$28.0M ▲ 80%Smart Red Blood Cells (Smart-RBC)$21.2M ▲ 431%Protean$15.7M ▲ 143%BioElectronics to Sense and Treat (BEST)$14.2M ▼ 15%Medics Autonomously Stopping Hemorrhage (MASH)$14.0M ▲ 52%
Novel Delivery Technology for Medical Countermeasures — this activity$12.1M ▼ 36%
Alert WARfighter Enablement (AWARE)$6.1M ▼ 50%
Reengineering Enabling Sleep Transitions in Operationally Restrictive Environments (RESTORE)$5.7M ▼ 12%
Controlled Genome Protection$5.4M ▼ 26%
Red Blood Cell Factory (RBC-Factory)$5.3M ▼ 47%
GOLDen hour extended EVACuation (GOLDEVAC)$4.9M ▼ 73%
Rapid Battlefield Triage▼ 100%
Next-Generation Combat Casualty Care▼ 100%
Source
FY2027 Office of the Secretary of Defense RDT&E Budget Justification · Exhibit R-2A · PE 0602024E, project WP-02 (President's Budget PB2027). Congressional marks are recorded on the program element, never on an activity.
Machine access
Markdown twin /programs/0602024E/WP-02/a1.md · MCP mcp.hitchintel.combudget_get_activity